FOXO1 orchestrates the bone-suppressing function of gut-derived serotonin.

Kode, Aruna

FOXO1 orchestrates the bone-suppressing function of gut-derived serotonin. [electronic resource] - The Journal of clinical investigation Oct 2012 - 3490-503 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1558-8238

10.1172/JCI64906 doi


Activating Transcription Factor 4--physiology
Animals
Blood-Brain Barrier
Bone Remodeling--physiology
Cell Division--drug effects
Cells, Cultured--drug effects
Cyclic AMP Response Element-Binding Protein--physiology
Duodenum--metabolism
Forkhead Box Protein O1
Forkhead Transcription Factors--deficiency
Gene Expression Regulation
Genes, Reporter
Genotype
Homeostasis--physiology
Insulin-Like Growth Factor I--genetics
Low Density Lipoprotein Receptor-Related Protein-5--deficiency
MAP Kinase Signaling System--drug effects
Mice
Organ Specificity
Osteoblasts--cytology
Osteogenesis--physiology
Promoter Regions, Genetic
Receptor, Serotonin, 5-HT1B--deficiency
Serotonin--blood
Stress, Physiological--genetics
Transcription, Genetic