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The determination and interpretation of the therapeutic index in drug development.

Muller, Patrick Y

The determination and interpretation of the therapeutic index in drug development. [electronic resource] - Nature reviews. Drug discovery Oct 2012 - 751-61 p. digital

Publication Type: Journal Article; Review

ISSN: 1474-1784

Standard No.: 10.1038/nrd3801 doi

Subjects--Topical Terms:
Animals
Biomarkers, Pharmacological--metabolism
Drug Discovery--trends
Drug-Related Side Effects and Adverse Reactions
Humans
Pharmaceutical Preparations--administration & dosage
Treatment Outcome

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