Secreted protein, acidic and rich in cysteine-like 1 (SPARCL1) is down regulated in aggressive prostate cancers and is prognostic for poor clinical outcome.

Hurley, Paula J

Secreted protein, acidic and rich in cysteine-like 1 (SPARCL1) is down regulated in aggressive prostate cancers and is prognostic for poor clinical outcome. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Sep 2012 - 14977-82 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1091-6490

10.1073/pnas.1203525109 doi


Animals
Calcium-Binding Proteins--metabolism
Cell Line, Tumor
Cell Movement--genetics
DNA Primers--genetics
Disease Progression
Extracellular Matrix Proteins--metabolism
Flow Cytometry
Fluorescent Antibody Technique
Gene Expression Regulation, Neoplastic--genetics
Humans
Immunoblotting
Immunohistochemistry
Male
Mice
Mice, Mutant Strains
Microarray Analysis
Models, Biological
Neoplasm Invasiveness--genetics
Neoplasm Recurrence, Local--metabolism
Prostatic Neoplasms--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Tetrazolium Salts
Thiazoles
rho GTP-Binding Proteins--metabolism
rhoC GTP-Binding Protein