Inhibitor of apoptosis protein (IAP) antagonists demonstrate divergent immunomodulatory properties in human immune subsets with implications for combination therapy.

Knights, Ashley J

Inhibitor of apoptosis protein (IAP) antagonists demonstrate divergent immunomodulatory properties in human immune subsets with implications for combination therapy. [electronic resource] - Cancer immunology, immunotherapy : CII Feb 2013 - 321-35 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1432-0851

10.1007/s00262-012-1342-1 doi


Antigens, Neoplasm--immunology
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cancer Vaccines--pharmacology
Cells, Cultured
Combined Modality Therapy
Cytokines--metabolism
Dendritic Cells--drug effects
Humans
Immunotherapy
Inhibitor of Apoptosis Proteins--antagonists & inhibitors
Leukocytes, Mononuclear--drug effects
NF-kappa B--metabolism
Peptides--pharmacology
T-Lymphocytes--drug effects
Thiazoles--pharmacology
Up-Regulation--drug effects