Rebuilding the balance of STAT1 and STAT3 signalings by fusaruside, a cerebroside compound, for the treatment of T-cell-mediated fulminant hepatitis in mice.

Wu, Xing-Xin

Rebuilding the balance of STAT1 and STAT3 signalings by fusaruside, a cerebroside compound, for the treatment of T-cell-mediated fulminant hepatitis in mice. [electronic resource] - Biochemical pharmacology Nov 2012 - 1164-73 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-2968

10.1016/j.bcp.2012.08.006 doi


Animals
CD4 Antigens--metabolism
Cell Proliferation--drug effects
Cerebrosides--isolation & purification
Concanavalin A
Cytokines--metabolism
Female
Fusarium--chemistry
Hepatitis, Animal--drug therapy
Liver--drug effects
Liver Failure, Acute--drug therapy
Lymphocyte Activation
Mice
Mice, Inbred C57BL
Natural Killer T-Cells--drug effects
STAT1 Transcription Factor--physiology
STAT2 Transcription Factor--physiology
Signal Transduction
Spleen--drug effects
T-Lymphocytes--drug effects
bcl-X Protein--metabolism