The evaluation of the reactivating and therapeutic efficacy of three novel bispyridinium oximes (K454, K456, K458) in comparison with the oxime K203 and trimedoxime in tabun-poisoned rats and mice.
Kassa, Jiri
The evaluation of the reactivating and therapeutic efficacy of three novel bispyridinium oximes (K454, K456, K458) in comparison with the oxime K203 and trimedoxime in tabun-poisoned rats and mice. [electronic resource] - Toxicology mechanisms and methods Feb 2013 - 94-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1537-6524
10.3109/15376516.2012.720304 doi
Acetylcholinesterase--metabolism
Animals
Brain--drug effects
Chemical Warfare Agents--poisoning
Cholinesterase Inhibitors--toxicity
Cholinesterase Reactivators--toxicity
Diaphragm--drug effects
Male
Mice
Mice, Inbred Strains
Organophosphates--toxicity
Pyridinium Compounds--toxicity
Rats
Rats, Wistar
Trimedoxime--toxicity
The evaluation of the reactivating and therapeutic efficacy of three novel bispyridinium oximes (K454, K456, K458) in comparison with the oxime K203 and trimedoxime in tabun-poisoned rats and mice. [electronic resource] - Toxicology mechanisms and methods Feb 2013 - 94-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1537-6524
10.3109/15376516.2012.720304 doi
Acetylcholinesterase--metabolism
Animals
Brain--drug effects
Chemical Warfare Agents--poisoning
Cholinesterase Inhibitors--toxicity
Cholinesterase Reactivators--toxicity
Diaphragm--drug effects
Male
Mice
Mice, Inbred Strains
Organophosphates--toxicity
Pyridinium Compounds--toxicity
Rats
Rats, Wistar
Trimedoxime--toxicity