Pharmacological inhibition of PHOSPHO1 suppresses vascular smooth muscle cell calcification.
Kiffer-Moreira, Tina
Pharmacological inhibition of PHOSPHO1 suppresses vascular smooth muscle cell calcification. [electronic resource] - Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Jan 2013 - 81-91 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1523-4681
10.1002/jbmr.1733 doi
2-Pyridinylmethylsulfinylbenzimidazoles--pharmacology
Alkaline Phosphatase--antagonists & inhibitors
Animals
Calcification, Physiologic--drug effects
Catalytic Domain
Computer Simulation
Enzyme Inhibitors--chemistry
Gene Expression Regulation--drug effects
Inhibitory Concentration 50
Lansoprazole
Mice
Models, Molecular
Muscle, Smooth, Vascular--pathology
Myocytes, Smooth Muscle--drug effects
Phosphoric Monoester Hydrolases--antagonists & inhibitors
RNA, Messenger--genetics
Substrate Specificity--drug effects
Vascular Calcification--enzymology
Pharmacological inhibition of PHOSPHO1 suppresses vascular smooth muscle cell calcification. [electronic resource] - Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Jan 2013 - 81-91 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1523-4681
10.1002/jbmr.1733 doi
2-Pyridinylmethylsulfinylbenzimidazoles--pharmacology
Alkaline Phosphatase--antagonists & inhibitors
Animals
Calcification, Physiologic--drug effects
Catalytic Domain
Computer Simulation
Enzyme Inhibitors--chemistry
Gene Expression Regulation--drug effects
Inhibitory Concentration 50
Lansoprazole
Mice
Models, Molecular
Muscle, Smooth, Vascular--pathology
Myocytes, Smooth Muscle--drug effects
Phosphoric Monoester Hydrolases--antagonists & inhibitors
RNA, Messenger--genetics
Substrate Specificity--drug effects
Vascular Calcification--enzymology