Induction of IL-4Rα-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo.
Rückerl, Dominik
Induction of IL-4Rα-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo. [electronic resource] - Blood Sep 2012 - 2307-16 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1528-0020
10.1182/blood-2012-02-408252 doi
Animals
Brugia malayi--immunology
Cell Line, Transformed
Cell Proliferation
Cells, Cultured
Gene Expression Profiling
Interleukin-4--metabolism
Interleukin-4 Receptor alpha Subunit--antagonists & inhibitors
Macrophage Activation
Macrophages--immunology
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Knockout
MicroRNAs--biosynthesis
Oligonucleotide Array Sequence Analysis
Phosphatidylinositol 3-Kinase--metabolism
Proto-Oncogene Proteins c-akt--genetics
RNA, Messenger--metabolism
Recombinant Proteins--metabolism
Signal Transduction
Up-Regulation
Induction of IL-4Rα-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo. [electronic resource] - Blood Sep 2012 - 2307-16 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1528-0020
10.1182/blood-2012-02-408252 doi
Animals
Brugia malayi--immunology
Cell Line, Transformed
Cell Proliferation
Cells, Cultured
Gene Expression Profiling
Interleukin-4--metabolism
Interleukin-4 Receptor alpha Subunit--antagonists & inhibitors
Macrophage Activation
Macrophages--immunology
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Knockout
MicroRNAs--biosynthesis
Oligonucleotide Array Sequence Analysis
Phosphatidylinositol 3-Kinase--metabolism
Proto-Oncogene Proteins c-akt--genetics
RNA, Messenger--metabolism
Recombinant Proteins--metabolism
Signal Transduction
Up-Regulation