Synthesis and evaluation of small libraries of triazolylmethoxy chalcones, flavanones and 2-aminopyrimidines as inhibitors of mycobacterial FAS-II and PknG.
Anand, Namrata
Synthesis and evaluation of small libraries of triazolylmethoxy chalcones, flavanones and 2-aminopyrimidines as inhibitors of mycobacterial FAS-II and PknG. [electronic resource] - Bioorganic & medicinal chemistry Sep 2012 - 5150-63 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3391
10.1016/j.bmc.2012.07.009 doi
Chalcones--chemical synthesis
Dose-Response Relationship, Drug
Enzyme Inhibitors--chemical synthesis
Fatty Acid Synthase, Type II--antagonists & inhibitors
Flavanones--chemical synthesis
Molecular Structure
Mycobacterium tuberculosis--enzymology
Protein Serine-Threonine Kinases--antagonists & inhibitors
Pyrimidines--chemical synthesis
Small Molecule Libraries--chemical synthesis
Structure-Activity Relationship
Triazoles--chemical synthesis
Synthesis and evaluation of small libraries of triazolylmethoxy chalcones, flavanones and 2-aminopyrimidines as inhibitors of mycobacterial FAS-II and PknG. [electronic resource] - Bioorganic & medicinal chemistry Sep 2012 - 5150-63 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3391
10.1016/j.bmc.2012.07.009 doi
Chalcones--chemical synthesis
Dose-Response Relationship, Drug
Enzyme Inhibitors--chemical synthesis
Fatty Acid Synthase, Type II--antagonists & inhibitors
Flavanones--chemical synthesis
Molecular Structure
Mycobacterium tuberculosis--enzymology
Protein Serine-Threonine Kinases--antagonists & inhibitors
Pyrimidines--chemical synthesis
Small Molecule Libraries--chemical synthesis
Structure-Activity Relationship
Triazoles--chemical synthesis