Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms.

Ibrahim, Elsayed E

Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms. [electronic resource] - Stem cells (Dayton, Ohio) Oct 2012 - 2076-87 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1549-4918

10.1002/stem.1182 doi


Adaptor Protein Complex 1--genetics
Animals
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors--genetics
Binding Sites
Cell Transformation, Neoplastic
Colorectal Neoplasms--genetics
Female
Gene Expression Regulation, Neoplastic
Homeodomain Proteins--genetics
Humans
JNK Mitogen-Activated Protein Kinases--genetics
Male
Mice
Nanog Homeobox Protein
Neoplasm Transplantation
Neoplastic Stem Cells--metabolism
Promoter Regions, Genetic
Protein Binding
Pseudogenes
Signal Transduction--genetics
Transcription Factor 4
Transcription Factors--genetics
Wnt Proteins--genetics
beta Catenin--genetics