Demethoxycurcumin modulates prostate cancer cell proliferation via AMPK-induced down-regulation of HSP70 and EGFR.

Hung, Chao-Ming

Demethoxycurcumin modulates prostate cancer cell proliferation via AMPK-induced down-regulation of HSP70 and EGFR. [electronic resource] - Journal of agricultural and food chemistry Aug 2012 - 8427-34 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-5118

10.1021/jf302754w doi


AMP-Activated Protein Kinases
Aminoimidazole Carboxamide--analogs & derivatives
Antineoplastic Agents, Phytogenic--pharmacology
Caspase 3--metabolism
Cell Line, Tumor
Cell Proliferation--drug effects
Curcuma--chemistry
Curcumin--analogs & derivatives
Diarylheptanoids
Down-Regulation
ErbB Receptors--metabolism
Fatty Acid Synthase, Type I--metabolism
HSP70 Heat-Shock Proteins--metabolism
Humans
Male
Phosphorylation--drug effects
Prostatic Neoplasms--drug therapy
Protein Tyrosine Phosphatase, Non-Receptor Type 11--antagonists & inhibitors
Proto-Oncogene Proteins c-cbl--metabolism
Ribonucleotides--pharmacology