The cardioprotection of simvastatin in reperfused swine hearts relates to the inhibition of myocardial edema by modulating aquaporins via the PKA pathway.

Li, Xiang-Dong

The cardioprotection of simvastatin in reperfused swine hearts relates to the inhibition of myocardial edema by modulating aquaporins via the PKA pathway. [electronic resource] - International journal of cardiology Sep 2013 - 2657-66 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1874-1754

10.1016/j.ijcard.2012.06.121 doi


Animals
Aquaporins--antagonists & inhibitors
Cardiotonic Agents--pharmacology
Cyclic AMP-Dependent Protein Kinases--antagonists & inhibitors
Edema--drug therapy
Myocardial Reperfusion Injury--drug therapy
Signal Transduction--drug effects
Simvastatin--pharmacology
Swine
Swine, Miniature