Mirtazapine inhibits tumor growth via immune response and serotonergic system.

Fang, Chun-Kai

Mirtazapine inhibits tumor growth via immune response and serotonergic system. [electronic resource] - PloS one 2012 - e38886 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0038886 doi


Adrenergic alpha-Antagonists--pharmacology
Animals
Autoradiography
Colonic Neoplasms--drug therapy
Genes, Reporter
Immunity, Innate--drug effects
Immunocompromised Host
Injections, Subcutaneous
Interferon-gamma--biosynthesis
Interleukin-12--biosynthesis
Luciferases
Male
Mianserin--analogs & derivatives
Mice
Mice, Inbred BALB C
Mice, SCID
Mirtazapine
Neoplasm Transplantation
Serotonin Plasma Membrane Transport Proteins--agonists
Survival Rate
T-Lymphocytes--drug effects
Tumor Microenvironment--drug effects
Tumor Necrosis Factor-alpha--biosynthesis