The combined strategy with PPARα agonism and AT₁ receptor antagonism is not superior relative to their individual treatment approach in preventing the induction of nephropathy in the diabetic rat.
Bishnoi, Harish Kumar
The combined strategy with PPARα agonism and AT₁ receptor antagonism is not superior relative to their individual treatment approach in preventing the induction of nephropathy in the diabetic rat. [electronic resource] - Pharmacological research Oct 2012 - 349-56 p. digital
Publication Type: Journal Article
1096-1186
10.1016/j.phrs.2012.07.001 doi
Angiotensin II Type 1 Receptor Blockers--pharmacology
Animals
Benzimidazoles--pharmacology
Benzoates--pharmacology
Blood Glucose--metabolism
Creatine--blood
Diabetes Mellitus--chemically induced
Diabetic Nephropathies--blood
Drug Therapy, Combination
Female
Fenofibrate--pharmacology
Hypolipidemic Agents--pharmacology
Kidney--drug effects
Lipids--blood
Male
Nitrogen--blood
Oxidative Stress--drug effects
PPAR alpha--agonists
Proteinuria--prevention & control
Rats
Rats, Wistar
Streptozocin
Telmisartan
The combined strategy with PPARα agonism and AT₁ receptor antagonism is not superior relative to their individual treatment approach in preventing the induction of nephropathy in the diabetic rat. [electronic resource] - Pharmacological research Oct 2012 - 349-56 p. digital
Publication Type: Journal Article
1096-1186
10.1016/j.phrs.2012.07.001 doi
Angiotensin II Type 1 Receptor Blockers--pharmacology
Animals
Benzimidazoles--pharmacology
Benzoates--pharmacology
Blood Glucose--metabolism
Creatine--blood
Diabetes Mellitus--chemically induced
Diabetic Nephropathies--blood
Drug Therapy, Combination
Female
Fenofibrate--pharmacology
Hypolipidemic Agents--pharmacology
Kidney--drug effects
Lipids--blood
Male
Nitrogen--blood
Oxidative Stress--drug effects
PPAR alpha--agonists
Proteinuria--prevention & control
Rats
Rats, Wistar
Streptozocin
Telmisartan