Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms.

Kumar, Anil

Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms. [electronic resource] - Brain research Aug 2012 - 13-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1872-6240

10.1016/j.brainres.2012.06.050 doi


Amphetamine
Analysis of Variance
Animals
Atorvastatin
Corpus Striatum--drug effects
Disease Models, Animal
Dose-Response Relationship, Drug
Drug Administration Schedule
Drug Interactions
Enzyme-Linked Immunosorbent Assay
Glutathione--metabolism
Heptanoic Acids--therapeutic use
Hydroxymethylglutaryl-CoA Reductase Inhibitors--therapeutic use
Interleukin-6--metabolism
Male
Malondialdehyde--metabolism
Mitochondria--drug effects
Motor Activity--drug effects
NADH Dehydrogenase--metabolism
Nitrites--metabolism
Oxidopamine--toxicity
Parkinsonian Disorders--chemically induced
Pyrroles--therapeutic use
Rats
Rats, Wistar
Simvastatin--therapeutic use
Tetrazolium Salts
Thiazoles
Tumor Necrosis Factor-alpha--metabolism