Apigenin prevents deregulation in the expression pattern of cell-proliferative, apoptotic, inflammatory and angiogenic markers during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.

Silvan, Simon

Apigenin prevents deregulation in the expression pattern of cell-proliferative, apoptotic, inflammatory and angiogenic markers during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis. [electronic resource] - Archives of oral biology Jan 2013 - 94-101 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-1506

10.1016/j.archoralbio.2012.06.005 doi


9,10-Dimethyl-1,2-benzanthracene--adverse effects
Angiogenesis Inhibitors--therapeutic use
Angiogenic Proteins--analysis
Animals
Anti-Inflammatory Agents--therapeutic use
Anticarcinogenic Agents--therapeutic use
Apigenin--therapeutic use
Apoptosis--drug effects
Carcinogens--pharmacology
Carcinoma, Squamous Cell--chemically induced
Caspase 3--drug effects
Caspase 9--drug effects
Cell Proliferation--drug effects
Cricetinae
Cyclin D1--drug effects
Cyclooxygenase 2--drug effects
Inflammation Mediators--analysis
Male
Mesocricetus
Mouth Neoplasms--chemically induced
NF-kappa B--drug effects
Proliferating Cell Nuclear Antigen--drug effects
Proto-Oncogene Proteins c-bcl-2--drug effects
Proto-Oncogene Proteins c-fos--drug effects
Tumor Suppressor Protein p53--drug effects
Vascular Endothelial Growth Factor A--drug effects
bcl-2-Associated X Protein--drug effects