Differential development of antinociceptive tolerance to morphine and fentanyl is not linked to efficacy in the ventrolateral periaqueductal gray of the rat.

Bobeck, Erin N

Differential development of antinociceptive tolerance to morphine and fentanyl is not linked to efficacy in the ventrolateral periaqueductal gray of the rat. [electronic resource] - The journal of pain Aug 2012 - 799-807 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1528-8447

10.1016/j.jpain.2012.05.005 doi


Analgesics, Opioid--pharmacology
Analysis of Variance
Animals
Dose-Response Relationship, Drug
Drug Interactions
Drug Tolerance--physiology
Fentanyl--pharmacology
Male
Microinjections
Morphine--pharmacology
Naltrexone--analogs & derivatives
Narcotic Antagonists--pharmacology
Pain Measurement--drug effects
Periaqueductal Gray--drug effects
Rats
Rats, Sprague-Dawley
Reaction Time--drug effects