Efficacy of EGFR inhibition is modulated by model, sex, genetic background and diet: implications for preclinical cancer prevention and therapy trials.

Rinella, Erica S

Efficacy of EGFR inhibition is modulated by model, sex, genetic background and diet: implications for preclinical cancer prevention and therapy trials. [electronic resource] - PloS one 2012 - e39552 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0039552 doi


Animals
Antineoplastic Agents--pharmacology
Azoxymethane--toxicity
Colorectal Neoplasms--chemically induced
Diet
Disease Models, Animal
ErbB Receptors--antagonists & inhibitors
Female
Male
Mice
Mice, Inbred C57BL
Phosphorylation
Quinazolines--pharmacology
Sex Factors
Tyrphostins--pharmacology