Thrombospondin-4 contributes to spinal sensitization and neuropathic pain states.

Kim, Doo-Sik

Thrombospondin-4 contributes to spinal sensitization and neuropathic pain states. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Jun 2012 - 8977-87 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1529-2401

10.1523/JNEUROSCI.6494-11.2012 doi


6-Cyano-7-nitroquinoxaline-2,3-dione
Analysis of Variance
Animals
Antibodies--therapeutic use
Disease Models, Animal
Excitatory Amino Acid Antagonists--pharmacology
Green Fluorescent Proteins--genetics
Humans
Hyperalgesia--metabolism
In Vitro Techniques
Inhibitory Postsynaptic Potentials--drug effects
Injections, Spinal
Male
Mice
Mice, Transgenic
Motor Activity--drug effects
Neuralgia--drug therapy
Oligodeoxyribonucleotides, Antisense--administration & dosage
Pain Measurement
Pain Threshold--drug effects
Rats
Rats, Sprague-Dawley
Sodium Channel Blockers--pharmacology
Spinal Cord--drug effects
Spinal Nerves--injuries
Tetrodotoxin--pharmacology
Thrombospondins--deficiency
Up-Regulation--drug effects
Valine--analogs & derivatives