Adipocyte hypertrophy is associated with lysosomal permeability both in vivo and in vitro: role in adipose tissue inflammation.

Gornicka, Agnieszka

Adipocyte hypertrophy is associated with lysosomal permeability both in vivo and in vitro: role in adipose tissue inflammation. [electronic resource] - American journal of physiology. Endocrinology and metabolism Sep 2012 - E597-606 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1522-1555

10.1152/ajpendo.00022.2012 doi


3T3-L1 Cells
Adipocytes--drug effects
Animals
Apoptosis--drug effects
Cathepsin B--antagonists & inhibitors
Cysteine Proteinase Inhibitors--pharmacology
Diet, High-Fat--adverse effects
Enzyme Activation--drug effects
Fatty Acids, Nonesterified--adverse effects
Hypertrophy
Lysosomes--drug effects
Macrophage Activation--drug effects
Macrophages--drug effects
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Mitochondria--drug effects
Molecular Targeted Therapy
Obesity--drug therapy
Permeability--drug effects
Protein Transport--drug effects