Moderate chemical modifications of WAY-100635 improve the selectivity for 5-HT1A versus D4 receptors.

Mangin, Floriane

Moderate chemical modifications of WAY-100635 improve the selectivity for 5-HT1A versus D4 receptors. [electronic resource] - Bioorganic & medicinal chemistry letters Jul 2012 - 4550-4 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1464-3405

10.1016/j.bmcl.2012.05.119 doi


Molecular Structure
Piperazines--chemistry
Pyridines--chemistry
Receptor, Serotonin, 5-HT1A--metabolism
Receptors, Dopamine D4--antagonists & inhibitors
Serotonin 5-HT1 Receptor Antagonists--chemistry
Structure-Activity Relationship