Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts.

Ghavami, S

Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts. [electronic resource] - Cell death & disease Jun 2012 - e330 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2041-4889

10.1038/cddis.2012.61 doi


Apoptosis
Autophagy
Caspase 7--metabolism
Caspase Inhibitors--pharmacology
Caspases, Initiator--metabolism
Cell Death
Cells, Cultured
Endoplasmic Reticulum--metabolism
Endoplasmic Reticulum Stress
Enzyme Activation
Fibroblasts--drug effects
Heart Atria--cytology
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Mevalonic Acid--metabolism
Myocardium--cytology
Signal Transduction
Simvastatin--pharmacology
Unfolded Protein Response--drug effects