Relating molecular properties and in vitro assay results to in vivo drug disposition and toxicity outcomes.

Sutherland, Jeffrey J

Relating molecular properties and in vitro assay results to in vivo drug disposition and toxicity outcomes. [electronic resource] - Journal of medicinal chemistry Jul 2012 - 6455-66 p. digital

Publication Type: Journal Article

1520-4804

10.1021/jm300684u doi


Absorption
Animals
Biological Availability
Drug Discovery--methods
Drug-Related Side Effects and Adverse Reactions
Female
Pharmaceutical Preparations--chemistry
Pharmacokinetics
Rats
Solubility
Thermodynamics