Hypouricemic effects of novel concentrative nucleoside transporter 2 inhibitors through suppressing intestinal absorption of purine nucleosides.

Hiratochi, Masahiro

Hypouricemic effects of novel concentrative nucleoside transporter 2 inhibitors through suppressing intestinal absorption of purine nucleosides. [electronic resource] - European journal of pharmacology Sep 2012 - 183-91 p. digital

Publication Type: Journal Article

1879-0712

10.1016/j.ejphar.2012.06.015 doi


Animals
Biological Transport--drug effects
COS Cells
Cebus
Chlorocebus aethiops
Dose-Response Relationship, Drug
Furans--chemistry
Gene Expression Regulation--drug effects
HeLa Cells
Humans
Inosine--metabolism
Intestinal Absorption--drug effects
Male
Membrane Transport Proteins--metabolism
Purine Nucleosides--metabolism
RNA, Fungal--administration & dosage
Rats
Rats, Sprague-Dawley
Renal Tubular Transport, Inborn Errors--blood
Uric Acid--blood
Urinary Calculi--blood