ERK1/2, p38, and JNK regulate the expression and the activity of the three isoforms of the Na+ /Ca2+ exchanger, NCX1, NCX2, and NCX3, in neuronal PC12 cells.

Sirabella, Rossana

ERK1/2, p38, and JNK regulate the expression and the activity of the three isoforms of the Na+ /Ca2+ exchanger, NCX1, NCX2, and NCX3, in neuronal PC12 cells. [electronic resource] - Journal of neurochemistry Sep 2012 - 911-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1471-4159

10.1111/j.1471-4159.2012.07838.x doi


Animals
CREB-Binding Protein--genetics
Calcium--metabolism
Cell Differentiation--drug effects
Chromatin Immunoprecipitation
Cyclic AMP--pharmacology
Dose-Response Relationship, Drug
Enzyme Inhibitors--pharmacology
Gene Expression Regulation, Enzymologic--drug effects
MAP Kinase Kinase 4
MAP Kinase Signaling System--drug effects
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinases--metabolism
Nerve Growth Factor--pharmacology
Nerve Tissue Proteins--metabolism
Neurons--drug effects
PC12 Cells--drug effects
Protein Isoforms--genetics
RNA, Small Interfering--pharmacology
Rats
Sodium-Calcium Exchanger--classification
Sp1 Transcription Factor--metabolism
Time Factors
p38 Mitogen-Activated Protein Kinases