Design, synthesis, and preliminary biological evaluation of 6-O-glucose-azomycin adducts for diagnosis and therapy of hypoxic tumors.
Kumar, Piyush
Design, synthesis, and preliminary biological evaluation of 6-O-glucose-azomycin adducts for diagnosis and therapy of hypoxic tumors. [electronic resource] - Journal of medicinal chemistry Jul 2012 - 6033-46 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4804
10.1021/jm2017336 doi
Cell Hypoxia
Cell Line, Tumor
Drug Design
Glucose Transport Proteins, Facilitative--antagonists & inhibitors
Glucosides--chemistry
Glycosides--chemical synthesis
Humans
Inhibitory Concentration 50
Magnetic Resonance Spectroscopy
Misonidazole--analogs & derivatives
Neoplasms--diagnostic imaging
Nitroimidazoles--chemical synthesis
Radiation-Sensitizing Agents--chemistry
Radionuclide Imaging
Radiopharmaceuticals--chemistry
Transcriptional Activation--drug effects
Design, synthesis, and preliminary biological evaluation of 6-O-glucose-azomycin adducts for diagnosis and therapy of hypoxic tumors. [electronic resource] - Journal of medicinal chemistry Jul 2012 - 6033-46 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4804
10.1021/jm2017336 doi
Cell Hypoxia
Cell Line, Tumor
Drug Design
Glucose Transport Proteins, Facilitative--antagonists & inhibitors
Glucosides--chemistry
Glycosides--chemical synthesis
Humans
Inhibitory Concentration 50
Magnetic Resonance Spectroscopy
Misonidazole--analogs & derivatives
Neoplasms--diagnostic imaging
Nitroimidazoles--chemical synthesis
Radiation-Sensitizing Agents--chemistry
Radionuclide Imaging
Radiopharmaceuticals--chemistry
Transcriptional Activation--drug effects