Sphingosine 1-phosphate receptor 2 antagonist JTE-013 increases the excitability of sensory neurons independently of the receptor.

Li, Chao

Sphingosine 1-phosphate receptor 2 antagonist JTE-013 increases the excitability of sensory neurons independently of the receptor. [electronic resource] - Journal of neurophysiology Sep 2012 - 1473-83 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1522-1598

10.1152/jn.00825.2011 doi


Action Potentials--drug effects
Analysis of Variance
Anilides--pharmacology
Animals
Capsaicin--pharmacology
Cell Line, Tumor
Cell Movement--drug effects
Dinoprostone--pharmacology
Dose-Response Relationship, Drug
Drug Interactions
Ganglia, Spinal--cytology
Guanosine Diphosphate--analogs & derivatives
Hyperalgesia--drug therapy
Lysophospholipids--pharmacology
Male
Melanoma--pathology
Mice
Organophosphonates--pharmacology
Pain Threshold--drug effects
Patch-Clamp Techniques
Pertussis Toxin--pharmacology
Pyrazoles--pharmacology
Pyridines--pharmacology
Rats
Rats, Sprague-Dawley
Receptors, Lysosphingolipid--antagonists & inhibitors
Sensory Receptor Cells--drug effects
Sensory System Agents--pharmacology
Sphingosine--analogs & derivatives
Thionucleotides--pharmacology
Time Factors
Wound Healing--drug effects