Synthesis and biological evaluation of antifungal derivatives of enfumafungin as orally bioavailable inhibitors of β-1,3-glucan synthase.
Heasley, Brian H
Synthesis and biological evaluation of antifungal derivatives of enfumafungin as orally bioavailable inhibitors of β-1,3-glucan synthase. [electronic resource] - Bioorganic & medicinal chemistry letters Nov 2012 - 6811-6 p. digital
Publication Type: Journal Article
1464-3405
10.1016/j.bmcl.2012.05.031 doi
Administration, Oral
Animals
Antifungal Agents--chemical synthesis
Candida albicans--drug effects
Enzyme Inhibitors--chemical synthesis
Glucosyltransferases--antagonists & inhibitors
Glycosides--chemical synthesis
Half-Life
Mice
Structure-Activity Relationship
Triterpenes--chemical synthesis
Synthesis and biological evaluation of antifungal derivatives of enfumafungin as orally bioavailable inhibitors of β-1,3-glucan synthase. [electronic resource] - Bioorganic & medicinal chemistry letters Nov 2012 - 6811-6 p. digital
Publication Type: Journal Article
1464-3405
10.1016/j.bmcl.2012.05.031 doi
Administration, Oral
Animals
Antifungal Agents--chemical synthesis
Candida albicans--drug effects
Enzyme Inhibitors--chemical synthesis
Glucosyltransferases--antagonists & inhibitors
Glycosides--chemical synthesis
Half-Life
Mice
Structure-Activity Relationship
Triterpenes--chemical synthesis