Impaired heat shock response in cells expressing full-length polyglutamine-expanded huntingtin.

Chafekar, Sidhartha M

Impaired heat shock response in cells expressing full-length polyglutamine-expanded huntingtin. [electronic resource] - PloS one 2012 - e37929 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0037929 doi


Animals
Blotting, Western
DNA-Binding Proteins--metabolism
Gene Knock-In Techniques
HSP70 Heat-Shock Proteins--metabolism
Heat Shock Transcription Factors
Heat-Shock Response--genetics
Huntingtin Protein
Huntington Disease--complications
Mice
Nerve Tissue Proteins--genetics
Nuclear Proteins--genetics
Peptides--genetics
Proteostasis Deficiencies--etiology
Transcription Factors--metabolism