Epigenetic regulation of 5-lipoxygenase in the phenotypic plasticity of valvular interstitial cells associated with aortic valve stenosis.

Nagy, Edit

Epigenetic regulation of 5-lipoxygenase in the phenotypic plasticity of valvular interstitial cells associated with aortic valve stenosis. [electronic resource] - FEBS letters May 2012 - 1325-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-3468

10.1016/j.febslet.2012.03.039 doi


Aortic Valve--drug effects
Aortic Valve Stenosis--genetics
Arachidonate 5-Lipoxygenase--genetics
Azacitidine--analogs & derivatives
DNA Methylation--drug effects
Decitabine
Epigenesis, Genetic--drug effects
Gene Expression Regulation, Enzymologic--drug effects
Humans
Leukotrienes--biosynthesis
Phenotype
Promoter Regions, Genetic--drug effects
Transcription, Genetic--drug effects