PI3K/Akt signaling pathway-induced heme oxygenase-1 upregulation mediates the adaptive cytoprotection of hydrogen peroxide preconditioning against oxidative injury in PC12 cells.

Mo, Liqiu

PI3K/Akt signaling pathway-induced heme oxygenase-1 upregulation mediates the adaptive cytoprotection of hydrogen peroxide preconditioning against oxidative injury in PC12 cells. [electronic resource] - International journal of molecular medicine Aug 2012 - 314-20 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1791-244X

10.3892/ijmm.2012.1002 doi


Animals
Cytoprotection--drug effects
Gene Expression
Heme Oxygenase-1--genetics
Hydrogen Peroxide--pharmacology
Oxidative Stress
PC12 Cells
Phosphatidylinositol 3-Kinases--metabolism
Phosphorylation--drug effects
Proto-Oncogene Proteins c-akt--metabolism
Rats
Signal Transduction
Up-Regulation--drug effects