A newly synthesized pyridine derivative, (Z)-5-methyl-2-[2-(1-naphthyl)ethenyl]-4-piperidinopyridine hydrochloride (AU-1421), as a reversible gastric proton pump inhibitor.

Hioki, Y

A newly synthesized pyridine derivative, (Z)-5-methyl-2-[2-(1-naphthyl)ethenyl]-4-piperidinopyridine hydrochloride (AU-1421), as a reversible gastric proton pump inhibitor. [electronic resource] - Archives internationales de pharmacodynamie et de therapie - 32-44 p. digital

Publication Type: Journal Article

0003-9780


Adenosine Triphosphatases--antagonists & inhibitors
Aminopyrine--metabolism
Animals
Cimetidine--pharmacology
Dogs
Gastric Mucosa--drug effects
Gastrins--pharmacology
Gastrointestinal Hormones--antagonists & inhibitors
H(+)-K(+)-Exchanging ATPase
In Vitro Techniques
Male
Naphthalenes--pharmacology
Proteins--metabolism
Pyridines--pharmacology
Rabbits
Rats
Rats, Inbred Strains
Swine