Improved risk assessment of endometrial cancer by combined analysis of MSI, PI3K-AKT, Wnt/β-catenin and P53 pathway activation.

Nout, Remi A

Improved risk assessment of endometrial cancer by combined analysis of MSI, PI3K-AKT, Wnt/β-catenin and P53 pathway activation. [electronic resource] - Gynecologic oncology Sep 2012 - 466-73 p. digital

Publication Type: Journal Article

1095-6859

10.1016/j.ygyno.2012.05.012 doi


Adaptor Proteins, Signal Transducing--genetics
Aged
Aged, 80 and over
Disease-Free Survival
Endometrial Neoplasms--genetics
Exons
Female
Humans
Kaplan-Meier Estimate
Methylation
Microsatellite Instability
Middle Aged
Multivariate Analysis
MutL Protein Homolog 1
Mutation
Neoplasm Recurrence, Local--metabolism
Nuclear Proteins--genetics
PTEN Phosphohydrolase--metabolism
Promoter Regions, Genetic
Proportional Hazards Models
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins c-akt--metabolism
Proto-Oncogene Proteins p21(ras)
Risk Assessment
Sequence Analysis, DNA
Transcription Factors--genetics
Tumor Suppressor Protein p53--genetics
Wnt Signaling Pathway--genetics
beta Catenin--metabolism
ras Proteins--genetics