Synthesis, biological evaluation, and molecular docking studies of N,1,3-triphenyl-1H-pyrazole-4-carboxamide derivatives as anticancer agents.

Li, Xi

Synthesis, biological evaluation, and molecular docking studies of N,1,3-triphenyl-1H-pyrazole-4-carboxamide derivatives as anticancer agents. [electronic resource] - Bioorganic & medicinal chemistry letters Jun 2012 - 3589-93 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1464-3405

10.1016/j.bmcl.2012.04.066 doi


Amides--chemical synthesis
Antineoplastic Agents--chemical synthesis
Apoptosis--drug effects
Aurora Kinases
Binding Sites
Cell Line, Tumor
Computer Simulation
HCT116 Cells
Humans
Protein Serine-Threonine Kinases--antagonists & inhibitors
Protein Structure, Tertiary
Pyrazoles--chemical synthesis