Overexpression of human HSP27 protects sensory neurons from diabetes.
Korngut, L
Overexpression of human HSP27 protects sensory neurons from diabetes. [electronic resource] - Neurobiology of disease Sep 2012 - 436-43 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1095-953X
10.1016/j.nbd.2012.04.017 doi
Age Factors
Analysis of Variance
Animals
Blood Glucose--drug effects
Caspase 3--metabolism
Diabetes Mellitus, Experimental--chemically induced
Disease Models, Animal
Female
Ganglia, Spinal--pathology
Gene Expression Regulation--drug effects
Glycated Hemoglobin--metabolism
HSP27 Heat-Shock Proteins--genetics
Humans
Hyperalgesia--genetics
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Mitogen-Activated Protein Kinases--metabolism
Nerve Fibers--metabolism
Neural Conduction--drug effects
Pain Threshold--physiology
Peripheral Nerves--pathology
Protein Serine-Threonine Kinases--metabolism
Sensory Receptor Cells--metabolism
Signal Transduction--drug effects
Skin--innervation
Streptozocin--pharmacology
Time Factors
NF-kappaB-Inducing Kinase
Overexpression of human HSP27 protects sensory neurons from diabetes. [electronic resource] - Neurobiology of disease Sep 2012 - 436-43 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1095-953X
10.1016/j.nbd.2012.04.017 doi
Age Factors
Analysis of Variance
Animals
Blood Glucose--drug effects
Caspase 3--metabolism
Diabetes Mellitus, Experimental--chemically induced
Disease Models, Animal
Female
Ganglia, Spinal--pathology
Gene Expression Regulation--drug effects
Glycated Hemoglobin--metabolism
HSP27 Heat-Shock Proteins--genetics
Humans
Hyperalgesia--genetics
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Mitogen-Activated Protein Kinases--metabolism
Nerve Fibers--metabolism
Neural Conduction--drug effects
Pain Threshold--physiology
Peripheral Nerves--pathology
Protein Serine-Threonine Kinases--metabolism
Sensory Receptor Cells--metabolism
Signal Transduction--drug effects
Skin--innervation
Streptozocin--pharmacology
Time Factors
NF-kappaB-Inducing Kinase