Human monoclonal antibodies targeting nonoverlapping epitopes on insulin-like growth factor II as a novel type of candidate cancer therapeutics.

Chen, Weizao

Human monoclonal antibodies targeting nonoverlapping epitopes on insulin-like growth factor II as a novel type of candidate cancer therapeutics. [electronic resource] - Molecular cancer therapeutics Jul 2012 - 1400-10 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Intramural

1538-8514

10.1158/1535-7163.MCT-12-0172 doi


Antibodies, Monoclonal--immunology
Antibody Affinity
Antibody Specificity
Antigen-Antibody Complex
Cell Communication--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Epitopes--immunology
Humans
Immunoglobulin G--immunology
Insulin-Like Growth Factor II--chemistry
Neoplasms--immunology
Phagocytosis--drug effects
Phosphorylation--drug effects
Protein Binding--drug effects
Receptor, IGF Type 1--metabolism
Receptors, IgG--metabolism