The metabotropic glutamate receptor 8 agonist (S)-3,4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson's disease.

Johnson, Kari A

The metabotropic glutamate receptor 8 agonist (S)-3,4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson's disease. [electronic resource] - Neuropharmacology Mar 2013 - 187-95 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1873-7064

10.1016/j.neuropharm.2012.03.029 doi


Aminobutyrates--administration & dosage
Animals
Benzoates--administration & dosage
Catalepsy--chemically induced
Disease Models, Animal
Dopamine--metabolism
Dopamine D2 Receptor Antagonists
Dose-Response Relationship, Drug
Dyskinesia, Drug-Induced--drug therapy
Excitatory Amino Acid Agonists--administration & dosage
Forelimb--drug effects
Glycine--administration & dosage
Haloperidol
Injections, Intraventricular
Male
Neostriatum--drug effects
Parkinsonian Disorders--drug therapy
Rats
Rats, Sprague-Dawley
Receptors, Dopamine D2--metabolism
Receptors, Metabotropic Glutamate--agonists
Reserpine
Time Factors