Synthesis, in vitro and in silico NS5B polymerase inhibitory activity of benzimidazole derivatives.

Patil, Vaishali M

Synthesis, in vitro and in silico NS5B polymerase inhibitory activity of benzimidazole derivatives. [electronic resource] - Medicinal chemistry (Shariqah (United Arab Emirates)) Jul 2012 - 629-35 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1875-6638

10.2174/157340612801216120 doi


Benzimidazoles--chemical synthesis
DNA-Directed RNA Polymerases--antagonists & inhibitors
Drug Design
Enzyme Activation--drug effects
Enzyme Inhibitors--chemical synthesis
Hepacivirus--drug effects
Humans
Inhibitory Concentration 50
Models, Molecular
Quantitative Structure-Activity Relationship
Structure-Activity Relationship
Viral Nonstructural Proteins--drug effects