Ethanol-mediated regulation of cytochrome P450 2A6 expression in monocytes: role of oxidative stress-mediated PKC/MEK/Nrf2 pathway.
Jin, Mengyao
Ethanol-mediated regulation of cytochrome P450 2A6 expression in monocytes: role of oxidative stress-mediated PKC/MEK/Nrf2 pathway. [electronic resource] - PloS one 2012 - e35505 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1932-6203
10.1371/journal.pone.0035505 doi
Active Transport, Cell Nucleus--drug effects
Aryl Hydrocarbon Hydroxylases--metabolism
Ascorbic Acid--pharmacology
Cytochrome P-450 CYP2A6
Cytochrome P-450 CYP2E1--metabolism
Enzyme Activation--drug effects
Ethanol--metabolism
Humans
Mitogen-Activated Protein Kinase Kinases--metabolism
Models, Biological
Monocytes--drug effects
NF-E2-Related Factor 2--metabolism
Oxidative Stress--drug effects
Protein Kinase C--metabolism
Signal Transduction--drug effects
U937 Cells
Ethanol-mediated regulation of cytochrome P450 2A6 expression in monocytes: role of oxidative stress-mediated PKC/MEK/Nrf2 pathway. [electronic resource] - PloS one 2012 - e35505 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1932-6203
10.1371/journal.pone.0035505 doi
Active Transport, Cell Nucleus--drug effects
Aryl Hydrocarbon Hydroxylases--metabolism
Ascorbic Acid--pharmacology
Cytochrome P-450 CYP2A6
Cytochrome P-450 CYP2E1--metabolism
Enzyme Activation--drug effects
Ethanol--metabolism
Humans
Mitogen-Activated Protein Kinase Kinases--metabolism
Models, Biological
Monocytes--drug effects
NF-E2-Related Factor 2--metabolism
Oxidative Stress--drug effects
Protein Kinase C--metabolism
Signal Transduction--drug effects
U937 Cells