PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques.
Dyavar Shetty, Ravi
PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques. [electronic resource] - The Journal of clinical investigation May 2012 - 1712-6 p. digital
Publication Type: Journal Article
1558-8238
10.1172/JCI60612 doi
Animals
Antibodies, Neutralizing--pharmacology
Antiviral Agents--pharmacology
Bacteremia--blood
Bacterial Translocation
Campylobacter--immunology
Chronic Disease
Feces--microbiology
Gene Expression Profiling
Humans
Interferon Type I--blood
Intestinal Mucosa--drug effects
Intestine, Large--drug effects
Lipopolysaccharides--blood
Macaca mulatta
Opportunistic Infections--microbiology
Programmed Cell Death 1 Receptor--antagonists & inhibitors
Salmonella--immunology
Shigella--immunology
Signal Transduction
Simian Acquired Immunodeficiency Syndrome--drug therapy
Simian Immunodeficiency Virus
Transcription, Genetic
Trichuris--immunology
PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques. [electronic resource] - The Journal of clinical investigation May 2012 - 1712-6 p. digital
Publication Type: Journal Article
1558-8238
10.1172/JCI60612 doi
Animals
Antibodies, Neutralizing--pharmacology
Antiviral Agents--pharmacology
Bacteremia--blood
Bacterial Translocation
Campylobacter--immunology
Chronic Disease
Feces--microbiology
Gene Expression Profiling
Humans
Interferon Type I--blood
Intestinal Mucosa--drug effects
Intestine, Large--drug effects
Lipopolysaccharides--blood
Macaca mulatta
Opportunistic Infections--microbiology
Programmed Cell Death 1 Receptor--antagonists & inhibitors
Salmonella--immunology
Shigella--immunology
Signal Transduction
Simian Acquired Immunodeficiency Syndrome--drug therapy
Simian Immunodeficiency Virus
Transcription, Genetic
Trichuris--immunology