O-linked glycosylation of von Willebrand factor modulates the interaction with platelet receptor glycoprotein Ib under static and shear stress conditions.

Nowak, Agata A

O-linked glycosylation of von Willebrand factor modulates the interaction with platelet receptor glycoprotein Ib under static and shear stress conditions. [electronic resource] - Blood Jul 2012 - 214-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1528-0020

10.1182/blood-2012-02-410050 doi


Anti-Bacterial Agents--pharmacology
Binding Sites--physiology
Blood Platelets--physiology
Collagen--metabolism
Genetic Variation
Glycosylation
HEK293 Cells
Humans
Membrane Glycoproteins--chemistry
Mutagenesis--physiology
Platelet Glycoprotein GPIb-IX Complex
Polysaccharides--metabolism
Protein Binding--drug effects
Protein Structure, Tertiary--physiology
Recombinant Proteins--metabolism
Regional Blood Flow--physiology
Ristocetin--pharmacology
Stress, Mechanical
von Willebrand Factor--chemistry