Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress.
Lee, In Hye
Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. [electronic resource] - Science (New York, N.Y.) Apr 2012 - 225-8 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
1095-9203
10.1126/science.1218395 doi
Animals
Apoptosis
Autophagy
Autophagy-Related Protein 7
Cell Cycle
Cell Cycle Checkpoints
Cell Line, Tumor
Cells, Cultured
Checkpoint Kinase 2
Cyclin-Dependent Kinase Inhibitor p21--genetics
DNA Damage
Gene Expression Regulation
Humans
Mice
Microtubule-Associated Proteins--genetics
Phosphorylation
Promoter Regions, Genetic
Protein Binding
Protein Multimerization
Protein Serine-Threonine Kinases--genetics
Stress, Physiological
Transcription, Genetic
Tumor Suppressor Protein p53--metabolism
Ubiquitin-Activating Enzymes--genetics
Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. [electronic resource] - Science (New York, N.Y.) Apr 2012 - 225-8 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
1095-9203
10.1126/science.1218395 doi
Animals
Apoptosis
Autophagy
Autophagy-Related Protein 7
Cell Cycle
Cell Cycle Checkpoints
Cell Line, Tumor
Cells, Cultured
Checkpoint Kinase 2
Cyclin-Dependent Kinase Inhibitor p21--genetics
DNA Damage
Gene Expression Regulation
Humans
Mice
Microtubule-Associated Proteins--genetics
Phosphorylation
Promoter Regions, Genetic
Protein Binding
Protein Multimerization
Protein Serine-Threonine Kinases--genetics
Stress, Physiological
Transcription, Genetic
Tumor Suppressor Protein p53--metabolism
Ubiquitin-Activating Enzymes--genetics