Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis.

Suragani, Rajasekhar N V S

Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis. [electronic resource] - Blood May 2012 - 5276-84 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1528-0020

10.1182/blood-2011-10-388132 doi


Activating Transcription Factor 4--genetics
Animals
Cell Differentiation--genetics
Cells, Cultured
Erythroblasts--metabolism
Erythropoiesis
Fetus--embryology
Globins--biosynthesis
Iron--metabolism
Iron Deficiencies
Liver--embryology
Mice
Mice, Knockout
Oxidative Stress
Protein Biosynthesis--genetics
Reactive Oxygen Species--metabolism
Signal Transduction
beta-Thalassemia--genetics
eIF-2 Kinase--genetics