From dynamic combinatorial 'hit' to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy.
Ofori, Leslie O
From dynamic combinatorial 'hit' to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy. [electronic resource] - Nucleic acids research Jul 2012 - 6380-90 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1362-4962
10.1093/nar/gks298 doi
Animals
Cell Line
Combinatorial Chemistry Techniques
Kinetics
Mice
Myotonic Dystrophy--genetics
Quinolines--chemistry
RNA--chemistry
RNA Splicing
RNA-Binding Proteins--metabolism
Thermodynamics
Trinucleotide Repeats
From dynamic combinatorial 'hit' to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy. [electronic resource] - Nucleic acids research Jul 2012 - 6380-90 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1362-4962
10.1093/nar/gks298 doi
Animals
Cell Line
Combinatorial Chemistry Techniques
Kinetics
Mice
Myotonic Dystrophy--genetics
Quinolines--chemistry
RNA--chemistry
RNA Splicing
RNA-Binding Proteins--metabolism
Thermodynamics
Trinucleotide Repeats