Methylation of death-associated protein kinase is associated with cetuximab and erlotinib resistance.

Ogawa, Takenori

Methylation of death-associated protein kinase is associated with cetuximab and erlotinib resistance. [electronic resource] - Cell cycle (Georgetown, Tex.) Apr 2012 - 1656-63 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1551-4005

10.4161/cc.20120 doi


Antibodies, Monoclonal--chemistry
Antibodies, Monoclonal, Humanized
Antineoplastic Agents--chemistry
Apoptosis Regulatory Proteins--antagonists & inhibitors
Calcium-Calmodulin-Dependent Protein Kinases--antagonists & inhibitors
Carcinoma, Non-Small-Cell Lung--enzymology
Carcinoma, Squamous Cell--enzymology
Cell Line, Tumor
Cetuximab
DNA Methylation--drug effects
Death-Associated Protein Kinases
Drug Resistance, Neoplasm
Erlotinib Hydrochloride
Head and Neck Neoplasms--enzymology
Humans
Lung Neoplasms--enzymology
Promoter Regions, Genetic
Quinazolines--chemistry
RNA Interference
RNA, Small Interfering--metabolism