KS370G, a synthetic caffeamide derivative, improves left ventricular hypertrophy and function in pressure-overload mice heart.

Weng, Yi-Chun

KS370G, a synthetic caffeamide derivative, improves left ventricular hypertrophy and function in pressure-overload mice heart. [electronic resource] - European journal of pharmacology Jun 2012 - 108-15 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-0712

10.1016/j.ejphar.2012.03.029 doi


Actins--metabolism
Angiotensin II--blood
Animals
Aorta--drug effects
Atrial Natriuretic Factor--blood
Caffeic Acids--pharmacology
Cardiotonic Agents--pharmacology
Collagen--metabolism
Constriction
Extracellular Signal-Regulated MAP Kinases--metabolism
Glycogen Synthase Kinase 3--metabolism
Glycogen Synthase Kinase 3 beta
Heart Ventricles--drug effects
Hypertrophy--drug therapy
L-Lactate Dehydrogenase--blood
Male
Mice
Mice, Inbred ICR
Myocytes, Cardiac--drug effects
Phosphoproteins--metabolism
Pressure--adverse effects
Proto-Oncogene Proteins c-akt--metabolism
Time Factors