Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients.
Breda, Laura
Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients. [electronic resource] - PloS one 2012 - e32345 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0032345 doi
Adult
Anemia, Sickle Cell--blood
Animals
Ankyrins--genetics
Antigens, CD34--metabolism
Base Sequence
Cell Differentiation--genetics
Cell Line, Tumor
Cells, Cultured
Erythroid Precursor Cells--metabolism
Gene Expression
Gene Transfer Techniques
Genetic Therapy--methods
Genetic Vectors--genetics
Hemoglobins--genetics
Humans
Insulator Elements--genetics
Lentivirus--genetics
Mice
Molecular Sequence Data
Mutation
NIH 3T3 Cells
beta-Globins--genetics
beta-Thalassemia--blood
Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients. [electronic resource] - PloS one 2012 - e32345 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0032345 doi
Adult
Anemia, Sickle Cell--blood
Animals
Ankyrins--genetics
Antigens, CD34--metabolism
Base Sequence
Cell Differentiation--genetics
Cell Line, Tumor
Cells, Cultured
Erythroid Precursor Cells--metabolism
Gene Expression
Gene Transfer Techniques
Genetic Therapy--methods
Genetic Vectors--genetics
Hemoglobins--genetics
Humans
Insulator Elements--genetics
Lentivirus--genetics
Mice
Molecular Sequence Data
Mutation
NIH 3T3 Cells
beta-Globins--genetics
beta-Thalassemia--blood