Glucocorticoid and cyclic adenosine 3'5'-monophosphate-mediated induction of cholesterol side-chain cleavage cytochrome P450 (P450scc) in MA-10 tumor Leydig cells. Increases in mRNA are cycloheximide sensitive.
Hales, D B
Glucocorticoid and cyclic adenosine 3'5'-monophosphate-mediated induction of cholesterol side-chain cleavage cytochrome P450 (P450scc) in MA-10 tumor Leydig cells. Increases in mRNA are cycloheximide sensitive. [electronic resource] - Endocrinology Jun 1990 - 2800-8 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0013-7227
10.1210/endo-126-6-2800 doi
8-Bromo Cyclic Adenosine Monophosphate--pharmacology
Cholesterol Side-Chain Cleavage Enzyme--biosynthesis
Cyclic AMP--pharmacology
Cycloheximide--pharmacology
DNA Probes
Dexamethasone--pharmacology
Estradiol--pharmacology
Gene Expression Regulation--drug effects
Leydig Cell Tumor--enzymology
Mifepristone--pharmacology
Nucleic Acid Hybridization
Progesterone--biosynthesis
RNA, Messenger--biosynthesis
Receptors, Glucocorticoid--physiology
Testosterone--pharmacology
Tumor Cells, Cultured
Glucocorticoid and cyclic adenosine 3'5'-monophosphate-mediated induction of cholesterol side-chain cleavage cytochrome P450 (P450scc) in MA-10 tumor Leydig cells. Increases in mRNA are cycloheximide sensitive. [electronic resource] - Endocrinology Jun 1990 - 2800-8 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0013-7227
10.1210/endo-126-6-2800 doi
8-Bromo Cyclic Adenosine Monophosphate--pharmacology
Cholesterol Side-Chain Cleavage Enzyme--biosynthesis
Cyclic AMP--pharmacology
Cycloheximide--pharmacology
DNA Probes
Dexamethasone--pharmacology
Estradiol--pharmacology
Gene Expression Regulation--drug effects
Leydig Cell Tumor--enzymology
Mifepristone--pharmacology
Nucleic Acid Hybridization
Progesterone--biosynthesis
RNA, Messenger--biosynthesis
Receptors, Glucocorticoid--physiology
Testosterone--pharmacology
Tumor Cells, Cultured