Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state.

Tiwari, Vijay K

Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Apr 2012 - E934-43 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

1091-6490

10.1073/pnas.1119798109 doi


Animals
Blotting, Western
Cell Differentiation--genetics
Cell Survival--genetics
Cells, Cultured
Chromatin--genetics
DNA Topoisomerases, Type II--genetics
DNA-Binding Proteins--antagonists & inhibitors
Diketopiperazines
Embryonic Stem Cells--cytology
Female
Gene Expression Profiling
Gene Expression Regulation, Developmental
Immunoprecipitation
Male
Mice
Mice, 129 Strain
Mice, Knockout
Neurons--cytology
Oligonucleotide Array Sequence Analysis
Piperazines--pharmacology
Protein Binding
RNA Interference
Receptor, Nerve Growth Factor--genetics
Reverse Transcriptase Polymerase Chain Reaction
Time Factors
Topoisomerase II Inhibitors--pharmacology