Negative argininosuccinate synthetase expression in melanoma tumours may predict clinical benefit from arginine-depleting therapy with pegylated arginine deiminase.

Feun, L G

Negative argininosuccinate synthetase expression in melanoma tumours may predict clinical benefit from arginine-depleting therapy with pegylated arginine deiminase. [electronic resource] - British journal of cancer Apr 2012 - 1481-5 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural

1532-1827

10.1038/bjc.2012.106 doi


Adult
Aged
Aged, 80 and over
Arginine--deficiency
Argininosuccinate Synthase--metabolism
Female
Humans
Hydrolases--therapeutic use
Liver Neoplasms--drug therapy
Lung Neoplasms--drug therapy
Male
Melanoma--drug therapy
Middle Aged
Polyethylene Glycols--therapeutic use
Skin Neoplasms--drug therapy
Survival Rate
Treatment Outcome